Germline mutations of aryl hydrocarbon receptor-interacting protein (AIP) gene and somatostatin receptor 1-5 and AIP immunostaining in patients with sporadic acromegaly with poor versus good response to somatostatin analogues

Ozkaya, Hande; Comunoglu, Nil; Sayitoglu, Müge; Keskin, Fatma; Firtina, Sinem; Khodzhaev, Khusan; Apaydin, Tugce; Gazioglu, Makbule; Tanriover, Necmettin; Oz, Ayşim; Kadioglu, Pınar

doi:10.1007/s11102-018-0876-4

Germline mutations of aryl hydrocarbon receptor-interacting protein (AIP) gene and somatostatin receptor 1-5 and AIP immunostaining in patients with sporadic acromegaly with poor versus good response to somatostatin analogues

Ozkaya H. M., Comunoglu N., Sayitoglu M., Keskin F. E., Firtina S., Khodzhaev K., ...Daha Fazla

PITUITARY, cilt.21, ss.335-346, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21
Basım Tarihi: 2018
Doi Numarası: 10.1007/s11102-018-0876-4
Dergi Adı: PITUITARY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.335-346
Anahtar Kelimeler: Somatostatin analogue, Receptor, Resistance, SECRETING PITUITARY-ADENOMAS, NEUROENDOCRINE TUMORS, SSTR2 EXPRESSION, OCTREOTIDE LAR, YOUNG-PATIENTS, SOMATOTROPINOMAS, PREVALENCE, RESISTANCE, COHORT, MACROADENOMAS
İstanbul Üniversitesi Adresli: Evet

Özet

Objective To determine aryl hydrocarbon interacting protein (AIP) gene variations and AIP and somatostatin receptor (SSTR) 1-5 immunostaining in patients with apparently sporadic acromegaly with poor versus good response to somatostatin analogues (SRLs).