Pelvic organ prolapse is descent of pelvic organs from their normal position. Several abdominal and vaginal operations have been designed for the treatment of pelvic organ prolapse. Native tissue or meshes can be used during these operations. Studies suggesting increased recurrence rate after plication with native tissue, have popularized the use of vaginal mesh surgery. Biologic and synthetic materials and mesh kits have been designed for this purpose. However, there is still debate about the indications of these procedures, short and long-term complications, and success rates.