Protective effect of a nuclear factor kappa B inhibitor, pyrolidium dithiocarbamate, in the kidney of rats with nephrolithiasis induced by ethylene glycol

Tugcu, Volkan; Ozbek, Emin; Kemahli, Eray; Cekmen, Mustafa; Caner, Nazli; Somay, Adnan; Erturkuner, Pelin; Seckin, İsmail; Demir, Cennet; Altug, Tuncay; Tasci, Ali

doi:10.1089/end.2007.0074

Protective effect of a nuclear factor kappa B inhibitor, pyrolidium dithiocarbamate, in the kidney of rats with nephrolithiasis induced by ethylene glycol

Tugcu V., Ozbek E., Kemahli E., Cekmen M. B., Caner N., Somay A., ...Daha Fazla

JOURNAL OF ENDOUROLOGY, cilt.21, sa.9, ss.1097-1106, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21 Sayı: 9
Basım Tarihi: 2007
Doi Numarası: 10.1089/end.2007.0074
Dergi Adı: JOURNAL OF ENDOUROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1097-1106
İstanbul Üniversitesi Adresli: Evet

Özet

Purpose: To study the protective effects of a selective nuclear factor kappa B (NF-kappa B) inhibitor, pyrolidium dithiocarbamate (PDTC), on ethylene glycol-induced crystal deposition in the renal tubules, renal toxicity, as well as inducible nitric oxide synthase (iNOS) and NF-kappa B activities in rat kidneys.