Protective effect of a nuclear factor kappa B inhibitor, pyrolidium dithiocarbamate, in the kidney of rats with nephrolithiasis induced by ethylene glycol

Tugcu V., Ozbek E., Kemahli E., Cekmen M. B. , Caner N., Somay A., ...More

JOURNAL OF ENDOUROLOGY, vol.21, no.9, pp.1097-1106, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 9
  • Publication Date: 2007
  • Doi Number: 10.1089/end.2007.0074
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1097-1106


Purpose: To study the protective effects of a selective nuclear factor kappa B (NF-kappa B) inhibitor, pyrolidium dithiocarbamate (PDTC), on ethylene glycol-induced crystal deposition in the renal tubules, renal toxicity, as well as inducible nitric oxide synthase (iNOS) and NF-kappa B activities in rat kidneys.