Idiopathic scrotal calcinosis is a very rare and benign disease characterized by asymptomatic, painless, and calcified nodules within the scrotal wall. A 44-year-old man presented with a 20-year history of scrotal nodules which had gradually increased in size and number, causing itching and slight pain. Physical examination revealed three very firm scrotal nodules with diameters of 4, 5, and 7 cm, respectively. Nodules were excised without any complication. Histopathological examination showed no epithelial lining or true cysts or cyst remnants and the diagnosis was made as idiopathic scrotal calcinosis. To our knowledge, the size of the biggest nodule also represents the largest nodule hitherto reported in the scrotum.