Impact of fingolimod on CD4+T cell subset and cytokine profile of relapsing remitting multiple sclerosis patients


Kurtuncu M. , Yilmaz V. , Akcay H. I. , Turkoglu R., Altunrende B., Cinar S. , ...Daha Fazla

JOURNAL OF NEUROIMMUNOLOGY, cilt.337, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Fingolimod inhibits the egress of lymphocytes from lymphatic tissues and also directly affects their functions by modulation of the sphingosine-1 -phosphate receptor 1 (S1P1). Our aim was to evaluate the impact of fingolimod on diverse CD4+ T cell subsets, and cytokines.