Apo E4 and lipoprotein-associated phospholipase A2 synergistically increase cardiovascular risk

Gungor Z., Anuurad E., Enkhmaa B., Zhang W., Kim K., Berglund L.

ATHEROSCLEROSIS, cilt.223, sa.1, ss.230-234, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 223 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.atherosclerosis.2012.04.021
  • Dergi Adı: ATHEROSCLEROSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.230-234
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Apolipoprotein E (apoE) has been implicated as conveying increased risk for coronary artery disease (CAD). Previous studies suggest a role of apoE as a modulator of immune response and inflammatory properties. We hypothesized that the presence of apo E-4 is associated with an increased inflammatory burden in subjects with CAD as compared to subjects without CAD.