A new coumarin based Schiff base fluorescence probe for zinc ion


ARVAS B., Ucar B., Acar T., Arvas M. B., ŞAHİN Y., AYDOĞAN F., ...More

TETRAHEDRON, vol.88, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 88
  • Publication Date: 2021
  • Doi Number: 10.1016/j.tet.2021.132127
  • Journal Name: TETRAHEDRON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, Veterinary Science Database, Index Chemicus (IC)
  • Keywords: Coumarin, Fluorescent probe, Chemosensor, Zinc ion detection, Cell imaging, SELECTIVE DETECTION, COLORIMETRIC PROBE, CHEMOSENSOR, ZN2+, DERIVATIVES, CADMIUM, PRECONCENTRATION, ENHANCEMENT, ELECTRODE, SENSORS
  • Istanbul University Affiliated: No

Abstract

Herein, a novel coumarin-based fluorescent probe (FS3) was designed, synthesized, and characterized. It exhibited significant fluorescence quenching in the presence of Zn2+ ions. Just a minor alteration occurred in the fluorescence intensity of FS3 in the presence of other metals studied. The limit of detection for the determination of Zn2+ by FS3 was calculated to be 3.43 x 10(-9) M. Since the Job's graph of 1/(F-0-F) and 1/[Zn2+] had a linear fit, it was determined that the binding stoichiometry between the FS3 and Zn2+ was 1:1. The association constant of the system was found to be 2.39 x 10(4) M-1 and confirmed by ESI-MS and FT-IR. It was demonstrated that the developed highly reversible sensor system works by performing real sample analysis. Moreover, the FS3 which has shown no toxicity and displayed a strong fluorescence image will act as an efficient and non-destructive sensor for the determination of Zn2+ in living organisms. (C) 2021 Elsevier Ltd. All rights reserved.