Superior consistency of ambulatory blood pressure monitoring in children: implications for clinical trials

Gimpel C., Wuehl E., Arbeiter K., Drozdz D., Trivelli A., Charbit M., ...Daha Fazla

JOURNAL OF HYPERTENSION, cilt.27, sa.8, ss.1568-1574, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 8
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1097/hjh.0b013e32832cb2a8
  • Dergi Adı: JOURNAL OF HYPERTENSION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1568-1574
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background Casual office blood pressure (CBP) measurements are still standard in antihypertensive drug trials. In pediatric hypertensive trials, ethical considerations, very low disease prevalence and the marked impact of white-coat hypertension create the need for very sensitive and reproducible techniques of BP assessment. We hypothesized that ambulatory BP monitoring (ABPM) may identify treatment effects more sensitively than CBP and thereby reduce sample sizes required in pediatric antihypertensive trials.