Paraoxonase-1 55/192 genotypes in schizophrenic patients and their relatives in Turkish population
Psychiatric Genetics, cilt.18, sa.6, ss.289-294, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 18 Sayı: 6
- Basım Tarihi: 2008
- Doi Numarası: 10.1097/ypg.0b013e3283060f94
- Dergi Adı: Psychiatric Genetics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.289-294
- Anahtar Kelimeler: oxidative stress, paraoxonase activity, paraoxonase polymorphism, relative, schizophrenia, LOW-DENSITY-LIPOPROTEIN, GAMMA-AMINOBUTYRIC ACID, THERAPEUTIC IMPLICATIONS, DIABETES-MELLITUS, OXIDATIVE STRESS, MOLECULAR-BASIS, FREE-RADICALS, RATING-SCALE, GENE PON1, SERUM
- İstanbul Üniversitesi Adresli: Evet
Özet
Background Oxidative stress and free radical-induced toxicity have been implicated in the pathophysiology of schizophrenia. In this study, we examined paraoxonase (PON1)-55/192 polymorphisms and PON1 activity in patients with schizophrenia, first-degree relatives of schizophrenic patients, and healthy controls.