Paraoxonase-1 55/192 genotypes in schizophrenic patients and their relatives in Turkish population

Kucukali C. İ., Aydin M., Ozkok E., Orhan N., Cakir U., KILIC G., ...Daha Fazla

Psychiatric Genetics, cilt.18, sa.6, ss.289-294, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1097/ypg.0b013e3283060f94
  • Dergi Adı: Psychiatric Genetics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.289-294
  • Anahtar Kelimeler: oxidative stress, paraoxonase activity, paraoxonase polymorphism, relative, schizophrenia, LOW-DENSITY-LIPOPROTEIN, GAMMA-AMINOBUTYRIC ACID, THERAPEUTIC IMPLICATIONS, DIABETES-MELLITUS, OXIDATIVE STRESS, MOLECULAR-BASIS, FREE-RADICALS, RATING-SCALE, GENE PON1, SERUM
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background Oxidative stress and free radical-induced toxicity have been implicated in the pathophysiology of schizophrenia. In this study, we examined paraoxonase (PON1)-55/192 polymorphisms and PON1 activity in patients with schizophrenia, first-degree relatives of schizophrenic patients, and healthy controls.