Diffusion-Weighted MR Imaging in the Differential Diagnosis of Adrenal Adenomas and Nonadenomatous Adrenal Masses

Bakir B., Salmaslioglu A., Guven K., Poyanli A., Kadioglu T. C.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.29, no.5, pp.1191-1197, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2009
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1191-1197
  • Istanbul University Affiliated: Yes


Objective: The aim of our study was to demonstrate the feasibility of body diffusion-weighted magnetic resonance (DW MR) imaging in the differential diagnosis of adrenal adenomas and non-adenomatous adrenal masses. Material and Methods: Thirty-seven adrenal masses in 32 consecutive patients (18 women, 14 men) were included in this prospective study. Of all the masses, 21 were adenomas and 16 were non-adenomatous adrenal masses. DW MR images were obtained by a body coil using a multisection single-shot echo planar sequence on the axial plane without breath holding (water excitation with b value of 50, 400 and 800 s/mm(2)). Signal intensities of the adenomas and non-adenomatous masses were measured for each b factor of 400 and 800 s/mm(2) using a region of interest (ROI). In addition, the signal intensities for apparent diffusion coefficient (ADC) calculation were measured. Mann Whitney U Test was used to compare signal intensities for each b factor (400 and 800 s/mm(2)) and for ADC values between the adenomas and non-adenomatous masses. Results: No significant difference was noted (p > 0.05) for ADC values between the two groups. Similarly, signal intensities with b factors of 400 and 800 s/mm(2) did not demonstrate a significant difference (p > 0.05) between the groups. Conclusion: DW MR imaging is not an effective method in the differential diagnosis of adenomatous and non-adenomatous lesions in adrenal glands.