Diffusion-Weighted MR Imaging in the Differential Diagnosis of Adrenal Adenomas and Nonadenomatous Adrenal Masses

Bakir B. , Salmaslioglu A. , Guven K., Poyanli A., Kadioglu T. C.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.29, no.5, pp.1191-1197, 2009 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2009
  • Page Numbers: pp.1191-1197


Objective: The aim of our study was to demonstrate the feasibility of body diffusion-weighted magnetic resonance (DW MR) imaging in the differential diagnosis of adrenal adenomas and non-adenomatous adrenal masses. Material and Methods: Thirty-seven adrenal masses in 32 consecutive patients (18 women, 14 men) were included in this prospective study. Of all the masses, 21 were adenomas and 16 were non-adenomatous adrenal masses. DW MR images were obtained by a body coil using a multisection single-shot echo planar sequence on the axial plane without breath holding (water excitation with b value of 50, 400 and 800 s/mm(2)). Signal intensities of the adenomas and non-adenomatous masses were measured for each b factor of 400 and 800 s/mm(2) using a region of interest (ROI). In addition, the signal intensities for apparent diffusion coefficient (ADC) calculation were measured. Mann Whitney U Test was used to compare signal intensities for each b factor (400 and 800 s/mm(2)) and for ADC values between the adenomas and non-adenomatous masses. Results: No significant difference was noted (p > 0.05) for ADC values between the two groups. Similarly, signal intensities with b factors of 400 and 800 s/mm(2) did not demonstrate a significant difference (p > 0.05) between the groups. Conclusion: DW MR imaging is not an effective method in the differential diagnosis of adenomatous and non-adenomatous lesions in adrenal glands.