14. International Trakya Family Medicine Congress , Edirne, Türkiye, 24 - 27 Nisan 2025, ss.61, (Özet Bildiri)
Aim: Lung cancer remains a leading cause of cancer-related mortality, yet early-stage cases often progress silently, detected only incidentally. Despite its potential to improve outcomes, national lung cancer screening programs are currently limited to a few countries, such as the Czech Republic, England, and Montenegro. Current guidelines primarily focus on symptomatic individuals or heavy smokers, overlooking a significant high-risk population. This study aims to evaluate the impact of risk factors—such as age, smoking history, sex, and family history—on lung cancer probability and advocate for a broader risk-based screening approach. Emerging evidence suggests that integrating such strategies could enhance early detection and improve survival in asymptomatic patients. Method: This retrospective study analyzed 68 patients who underwent anatomical lung resection for early-stage lung cancer at Istanbul University, Istanbul Faculty of Medicine, between 2022 and 2025. Results: A total of 68 patients who underwent anatomical lung resection for early-stage lung cancer were analyzed. The median age was 63 years (IQR: 31–78), with 64.7% being male. Smoking history was available for 50 patients, with a median exposure of 40 pack-years. Among all cases, 35.3% exhibited symptoms, with cough (20.6%) being the most common, followed by dyspnea (5.9%), chest pain (5.9%), and hemoptysis (2.9%). Smokers comprised 73.5% of the cohort. Conclusions: Early-stage lung cancer often progresses asymptomatically, as reflected in our cohort, where most of the patients were asymptomatic at diagnosis. Despite the predominance of smokers, current screening guidelines may overlook high-risk individuals. Our findings highlight the need for risk-based screening strategies incorporating age, sex, and smoking history to enhance early detection and improve outcomes.