Impact of Topiramate on Rat Phrenic Nerve-Hemidiaphragm Preparations

Kucukali C. I., Tuzun E., NURTEN A.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, vol.54, no.3, pp.202-204, 2017 (SCI-Expanded) identifier identifier identifier


Introduction: Topiramate has a negative modulatory effect on voltage-gated ion channels involved in neuromuscular junction transmission. To investigate the potential impact of topiramate on muscle contraction, phrenic nerve-hemidiaphragm preparations were used as a neuromuscular junction model.