Impact of Topiramate on Rat Phrenic Nerve-Hemidiaphragm Preparations

Kucukali C. I. , Tuzun E. , NURTEN A.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.54, ss.202-204, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 54 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/npa.2017.19422
  • Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Sayfa Sayıları: ss.202-204

Özet

Introduction: Topiramate has a negative modulatory effect on voltage-gated ion channels involved in neuromuscular junction transmission. To investigate the potential impact of topiramate on muscle contraction, phrenic nerve-hemidiaphragm preparations were used as a neuromuscular junction model.