Endocan: a novel predictor of endothelial dysfunction in obstructive sleep apnea syndrome

Kanbay A., Ceylan E., İNÖNÜ KÖSEOĞLU H., ÇALIŞKAN M., Takir M., Tulu S., ...Daha Fazla

CLINICAL RESPIRATORY JOURNAL, cilt.12, sa.1, ss.84-90, 2018 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/crj.12487
  • Dergi Adı: CLINICAL RESPIRATORY JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.84-90
  • Anahtar Kelimeler: endocan, endothelial dysfunction, obstructive sleep apnea, CIRCULATING ICAM-1, RISK, HYPERTENSION, EXPRESSION, MOLECULE-1, MORTALITY, PRESSURE, MEDIATOR, VCAM-1, MARKER
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background and Aims: Obstructive sleep apnea syndrome (OSA) is an independent risk factor for endothelial dysfunction and cardiometabolic diseases. Plasma endocan levels are elevated in a large number of diseases, and is a novel surrogate endothelial cell dysfunction marker. We aimed to assess the role of serum endocan level as a potential mechanism of endothelial dysfunction in OSA patients.