Endocan: a novel predictor of endothelial dysfunction in obstructive sleep apnea syndrome

Kanbay A., Ceylan E., İNÖNÜ KÖSEOĞLU H., ÇALIŞKAN M., Takir M., Tulu S., ...More

CLINICAL RESPIRATORY JOURNAL, vol.12, no.1, pp.84-90, 2018 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.1111/crj.12487
  • Journal Name: CLINICAL RESPIRATORY JOURNAL
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.84-90
  • Keywords: endocan, endothelial dysfunction, obstructive sleep apnea, CIRCULATING ICAM-1, RISK, HYPERTENSION, EXPRESSION, MOLECULE-1, MORTALITY, PRESSURE, MEDIATOR, VCAM-1, MARKER

Abstract

Background and Aims: Obstructive sleep apnea syndrome (OSA) is an independent risk factor for endothelial dysfunction and cardiometabolic diseases. Plasma endocan levels are elevated in a large number of diseases, and is a novel surrogate endothelial cell dysfunction marker. We aimed to assess the role of serum endocan level as a potential mechanism of endothelial dysfunction in OSA patients.