Does HepPar-1 immunoexpression have a role in differential diagnosis of periampullary cancer?

Gulluoglu M. G. , Karayigit E. , Ozden I. , Kapran Y. , Dizdaroglu F.

PATHOLOGY, cilt.40, ss.35-41, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 40 Konu: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1080/00313020701716391
  • Dergi Adı: PATHOLOGY
  • Sayfa Sayıları: ss.35-41


Aims: Histological subtyping of periampullary carcinomas is considered as a criterion for prognosis and therapeutic implications of these tumours. We assessed the immunoexpression rates of HepPar-1, CDX2 and MUC2 antibodies in different subtypes of periampullary adenocarcinomas (PAC), intestinal and pancreatobiliary, in order to assess their impact on differential diagnosis of this group of cancers. The expression of antibodies was also measured in ductal adenocarcinoma of the pancreatic head (DAPH).