Granzyme B Gene Polymorphism Associated with Subacute Sclerosing Panencephalitis


Yentur S. P. , Aydin H. N. , Gurses C., Demirbilek V. , KURU U., Uysal S., ...Daha Fazla

NEUROPEDIATRICS, cilt.45, ss.309-313, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 45 Konu: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1055/s-0034-1378129
  • Dergi Adı: NEUROPEDIATRICS
  • Sayfa Sayıları: ss.309-313

Özet

Background Subacute sclerosing panencephalitis (SSPE) is a late complication of measles infection. Immune dysfunction related to genetic susceptibility has been considered in disease pathogenesis. A functional single nucleotide polymorphism (SNP) of granzyme B gene (GZMB) reported in several pathologies may also be involved in susceptibility to SSPE.