HLA-DRB1*03 is a susceptibility gene in patients with Graves' disease with and without ophthalmopathy


YARMAN S., Oguz F., CARIN M. N.

INTERNATIONAL JOURNAL OF IMMUNOGENETICS, cilt.34, sa.1, ss.23-25, 2007 (SCI-Expanded) identifier identifier identifier

Özet

We sought an association between certain human leucocyte antigen (HLA) markers and Graves' disease (GD) with and without ophthalmopathy (OP). One hundred and thirty-one Turkish patients with GD (50 without OP, 81 with OP) and 250 local healthy controls were studied. HLA-DRB1 typing was performed by using polymerase chain reaction-sequence-specific primers (PCR-SSP) method.