HLA-DRB1*03 is a susceptibility gene in patients with Graves' disease with and without ophthalmopathy

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YARMAN S., Oguz F., CARIN M. N.

INTERNATIONAL JOURNAL OF IMMUNOGENETICS, vol.34, no.1, pp.23-25, 2007 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 34 Issue: 1
• Publication Date: 2007
• Doi Number: 10.1111/j.1744-313x.2006.00644.x
• Journal Name: INTERNATIONAL JOURNAL OF IMMUNOGENETICS
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.23-25
• Istanbul University Affiliated: Yes

Abstract

We sought an association between certain human leucocyte antigen (HLA) markers and Graves' disease (GD) with and without ophthalmopathy (OP). One hundred and thirty-one Turkish patients with GD (50 without OP, 81 with OP) and 250 local healthy controls were studied. HLA-DRB1 typing was performed by using polymerase chain reaction-sequence-specific primers (PCR-SSP) method.