Clinical and polysomnographic features of a large Turkish pedigree with restless leg syndrome and periodic limb movements

BABACAN YILDIZ G., Gursoy E., KOLUKISA M., Karakose F., Akkoyunlu E. M., Celebi A., ...More

SLEEP AND BREATHING, vol.17, no.2, pp.741-746, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1007/s11325-012-0756-5
  • Journal Name: SLEEP AND BREATHING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.741-746
  • Istanbul University Affiliated: Yes

Abstract

Restless leg syndrome (RLS) and periodic limb movements (PLMS) are common neurological diseases often associated with insomnia. A familial aggregation in RLS has been identified since it was first described; however, inheritance patterns of RLS/PLMS are poorly understood and their exact pathophysiology is not well-known. We have identified a Turkish pedigree with RLS/PLMS, which is a rare condition, in five generations of a family, including nine affected family members.