Bimodal Pattern of Coronary Microvascular Involvement in Diabetes Mellitus

Sezer, Murat; Kocaaga, Mehmet; Aslanger, Emre; Atici, Adem; Demirkiran, Ahmet; Bugra, Melike; Umman, Sabahattin; Umman, Berrin

doi:10.1161/jaha.116.003995

Bimodal Pattern of Coronary Microvascular Involvement in Diabetes Mellitus

Sezer M., Kocaaga M., Aslanger E., Atici A., Demirkiran A., Bugra Z., ...Daha Fazla

JOURNAL OF THE AMERICAN HEART ASSOCIATION, cilt.5, sa.11, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 5 Sayı: 11
Basım Tarihi: 2016
Doi Numarası: 10.1161/jaha.116.003995
Dergi Adı: JOURNAL OF THE AMERICAN HEART ASSOCIATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
İstanbul Üniversitesi Adresli: Evet

Özet

Background-The contribution of functionally disturbed coronary autoregulation and structurally impaired microvascular vasodilatory function to reduced coronary flow velocity reserve, reflecting impaired coronary microcirculation in diabetes mellitus (DM), has not been clearly elucidated. The objective of this study was to identify the mechanism of coronary microvascular impairment in DM in relation to duration of disease.