Comparison of antagonist mild and long agonist protocols in terms of follicular fluid total antioxidant capacity
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, vol.57, no.2, pp.194-199, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 57 Issue: 2
- Publication Date: 2018
- Doi Number: 10.1016/j.tjog.2018.02.005
- Journal Name: TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.194-199
- Istanbul University Affiliated: Yes
Abstract
Objective: A high dose of prolonged gonadotropins can yield higher numbers of oocytes and embryos. The high dose or prolonged regimens can be associated with ovarian hyperstimulation syndrome (OHSS), multiple gestations, emotional stress, economical burden and treatment dropout. In mild stimulation lower doses and shorter duration times of gonadotropin are used in contrast to the conventional long stimulation protocol in IVF. It has been proposed that supraphysiologic levels of hormones may adversely affect endometrium and oocyte/embryo. Also it has been proposed that oxidative stress (OS) may alter ovarian hormone dynamics and could be further affected by additional exogenous hormonal stimulation. Therefore our aim was to compare follicular fluid total antioxidant capacity (TAC) in antagonist mild and long agonist stimulations.