Statin-induced calcific Achilles tendinopathy in rats: comparison of biomechanical and histopathological effects of simvastatin, atorvastatin and rosuvastatin


Kaleagasioglu F., Olcay E., Olgac V.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, cilt.25, ss.1884-1891, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 25 Konu: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s00167-015-3728-z
  • Dergi Adı: KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
  • Sayfa Sayıları: ss.1884-1891

Özet

Accumulating clinical evidence indicates the risk of tendinopathy and spontaneous and/or simultaneous tendon ruptures associated with statin use. This experimental study was designed to evaluate and compare the biomechanical and histopathological effects of the three most commonly prescribed statins (simvastatin, atorvastatin and rosuvastatin) on the Achilles tendon in rats.