A rare side effect of vagal nerve stimulation: increased seizures and status epilepticus

Kizilkilic E. K., TANRIVERDİ T., YENİ S. N.

ACTA NEUROLOGICA BELGICA, 2026 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Letter
  • Publication Date: 2026
  • Doi Number: 10.1007/s13760-026-03009-9
  • Journal Name: ACTA NEUROLOGICA BELGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Istanbul University Affiliated: No

Abstract

Background Vagus nerve stimulation (VNS) is a neuromodulatory therapeutic option for drug-resistant epilepsy. Case Report We present two patients, aged 23 and 29 years, with drug-resistant epilepsy who experienced increased seizures and status epilepticus after application of VNS. Conclusion VNS is generally well tolerated and provides benefits for patients. However, both patients and their families and clinicians should be alert to the rare side effect of triggering seizures.