Amantadine monotherapy of chronic hepatitis C patients infected with genotype 1b

Senturk H., Mert A., Akdogan M., Tabak F., Basaran G., Turkoglu S., ...More

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, vol.32, no.5, pp.575-576, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 5
  • Publication Date: 2000
  • Journal Name: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.575-576
  • Istanbul University Affiliated: Yes

Abstract

We aimed to test the efficacy of amantadine in chronic hepatitis C (CHC) patients infected with genotype Ib. Twenty patients completed treatment with amantadine HCl, 100 mg b.i.d., for 6 months. Non-sustained biochemical improvement was observed without loss of HCV-RNA, We conclude that amantadine monotherapy is not effective in CHC.