Squamous Cell Carcinoma Mimicking Neck Paraganglioma on Ga-68-DOTATATE PET/CT

Civan C., Isik E. G., Has Simsek D., Sen C., Unal S. N.

CLINICAL NUCLEAR MEDICINE, cilt.46, sa.7, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 46 Sayı: 7
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1097/rlu.0000000000003555
  • Dergi Adı: CLINICAL NUCLEAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Anahtar Kelimeler: squamous cell carcinoma, larynx, Ga-68-DOTATATE, PET/CT, HEAD
  • İstanbul Üniversitesi Adresli: Evet

Özet

Somatostatin receptor (SSTR) imaging with Ga-68-labeled somatostatin analogs has been used for many tumors with high SSTR expression. Increased uptake mostly depends on the SSTR status of tumors; however, false-positive uptake can be demonstrated in benign diseases or other malignancies because of the increased SSTR expression. We present a case of a 50-year-old man with increased SSTR activity on cervical lesion located in internal jugular chain in Ga-68-DOTATATE PET/CT, which was performed for suspicion of paraganglioma. Biopsy revealed lymph node metastasis of squamous cell carcinoma other than paraganglioma. F-18-FDG PET/CT showed primary malignancy on larynx and lymph node metastasis, which were correlated surgically.