IGF-1 AND IGFBP-3 IN COLORECTAL CANCER, AN OBSERVATIONAL CASE-CONTROL STUDY

Bademler S., ZİRTİLOĞLU A., Sari M., Yasasever C., Karabulut S.

ACTA MEDICA MEDITERRANEA, vol.35, no.1, pp.15-21, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.19193/0393-6384_2019_1_1
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.15-21
  • Istanbul University Affiliated: Yes

Abstract

Introduction: Plasma levels of Insulin-Like Growth Factor-1 (IGF-1) and Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3) have been studied in terms of colorectal cancer formation and prognosis, until now. However, these studies have conflicting results. We aimed to contribute to the debate about whether serum IGF-1 and IGFBP-3 levels act on the colorectal cancer diagnosis and prognosis.