IGF-1 AND IGFBP-3 IN COLORECTAL CANCER, AN OBSERVATIONAL CASE-CONTROL STUDY
ACTA MEDICA MEDITERRANEA, vol.35, no.1, pp.15-21, 2019 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 35 Issue: 1
- Publication Date: 2019
- Doi Number: 10.19193/0393-6384_2019_1_1
- Journal Name: ACTA MEDICA MEDITERRANEA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.15-21
- Istanbul University Affiliated: Yes
Abstract
Introduction: Plasma levels of Insulin-Like Growth Factor-1 (IGF-1) and Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3) have been studied in terms of colorectal cancer formation and prognosis, until now. However, these studies have conflicting results. We aimed to contribute to the debate about whether serum IGF-1 and IGFBP-3 levels act on the colorectal cancer diagnosis and prognosis.