Synthesis, structure elucidation and antimicrobial activity of some 3-hydroxy-2-naphthoic acid hydrazide derivatives


Dogan H., Rollas S., Erdeniz H.

FARMACO, cilt.53, sa.7, ss.462-467, 1998 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 7
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1016/s0014-827x(98)00049-4
  • Dergi Adı: FARMACO
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.462-467
  • İstanbul Üniversitesi Adresli: Hayır

Özet

In this study, some 1,4-disubstituted thiosemicarbazide, 1,2,4-triazole and 1,3,4-thiadiazole type novel compounds derived from 3-hydroxy-2-naphthoic acid hydrazide were synthesized to screen for their antimicrobial activity. The structures of these substances were elucidated using elemental analysis and UV, H-1 NMR, and mass spectral methods. All of these compounds were tested in vitro for their antibacterial and antifungal activity. (C) 1998 Elsevier Science S.A. All rights reserved.