Cyclosporine-associated hyperkalemia: Report of four allogeneic blood stem-cell transplant cases
Transplantation, cilt.75, sa.7, ss.1069-1072, 2003 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 75 Sayı: 7
- Basım Tarihi: 2003
- Doi Numarası: 10.1097/01.tp.0000057241.69355.59
- Dergi Adı: Transplantation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1069-1072
- İstanbul Üniversitesi Adresli: Hayır
Özet
Background. Nephrotoxicity is a well-known effect of cyclosporine (CsA) that causes a reduction in glomerular filtration rate through vasoconstriction of the afferent glomerular arterioles and may result in acute renal failure. Isolated CsA-induced hyperkalemia occurring through different mechanisms is also common. However, there are only a few "case reports" addressing this phenomenon in allogeneic bone marrow transplantation patients. In this report, we propose mechanisms and methods of managing CsA-associated hyperkalemia in allogeneic transplantation.