The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats


Karaoglan A., Akdemir O., Barut S., Kokturk S. , Uzun H. , Tasyurekli M., ...Daha Fazla

SURGICAL NEUROLOGY, cilt.70, ss.337-343, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 70 Konu: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.surneu.2007.07.031
  • Dergi Adı: SURGICAL NEUROLOGY
  • Sayfa Sayıları: ss.337-343

Özet

Background: Cerebral vasospasin remains a major cause of morbidity and mortality in patients with SAH. Although many pharmacologic agents and chemicals have been used to prevent and treat CV, the pathogenesis of that condition has not been established. We investigated the efficacy of resveratrol, a stilbene polyphenol and tyrosine kinase inhibitor that occurs naturally in grapes and red wine, in a murine basilar artery vasospasm model.