Utility of P2Y12 Reactive Unit Assessment on Ticagrelor in Cerebral Aneurysms Treated with Intracranial Stenting and Flow Diversion: Cohort Study and Case Report From Two Neurovascular Centers

Bohan, Christian; Wirtz, Mirja; Hendrix, Philipp; Goren, Oded; Schirmer, Clemens; Islak, Civan; Grassi, Dante; Dalal, Shamsher; Weiner, Gregory; Griessenauer, Christoph

doi:10.1016/j.wneu.2020.07.052

Utility of P2Y12 Reactive Unit Assessment on Ticagrelor in Cerebral Aneurysms Treated with Intracranial Stenting and Flow Diversion: Cohort Study and Case Report From Two Neurovascular Centers

Bohan C. O., Wirtz M. M., Hendrix P., Goren O., Schirmer C. M., Islak C., ...More

WORLD NEUROSURGERY, vol.142, 2020 (SCI-Expanded)

Publication Type: Article / Article
Volume: 142
Publication Date: 2020
Doi Number: 10.1016/j.wneu.2020.07.052
Journal Name: WORLD NEUROSURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Index Islamicus, MEDLINE, Veterinary Science Database
Istanbul University Affiliated: Yes

Abstract

BACKGROUND: Dual antiplatelet therapy consisting of aspirin and clopidogrel is the standard of care for neuro-interventional stenting and flow diversion. Platelet function testing has been increasingly performed to identify patients with a hypo- or hyper-response to clopidogrel. Ticagrelor has been a popular alternative antiplatelet agent for such patients. We assessed the role of platelet function testing in patients receiving ticagrelor and undergoing stenting or flow diversion.