The aim of this study was to investigate possible associations between the accuracy of intermaxillary relations and complete denture usage 3 months and 3 years after their insertion. A total of 600 patients were provided with new complete dentures. Willis gauge and Woelfel's method were used to assess the quality of the existing complete dentures and the use of these dentures. Three years after insertion the remaining 250 patients took part in a follow-up examination. Three months post-insertion, significant relationships were found between adequate interocclusal rest space or quality of registration of centric relation and daily wearing of complete dentures and between quality of registration of centric relation and use of dentures for eating. Three years after insertion the adaptation to denture wearing was generally satisfactory. However, no significant relationship was observed between the accuracy of intermaxillary relations and complete denture usage.