Antifungal Activity of Caspofungin in Combination with Amphotericin B against Candida glabrata: Comparison of Disk Diffusion, Etest, and Time-Kill Methods

Kiraz N., Dag I., Yamac M., Kiremitci A., Kasifoglu N., Akgun Y.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol.53, no.2, pp.788-790, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1128/aac.01131-08
  • Journal Name: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.788-790
  • Istanbul University Affiliated: No

Abstract

The in vitro activities of caspofungin plus amphotericin B against 50 Candida glabrata isolates were evaluated by the time-kill, disk diffusion, and Etest methods. In vitro experiments showed a positive interaction. Even though each of these methods uses different conditions and endpoints, the results of the different methods frequently agreed.