Ventricular pre-excitation and cardiac hypertrophy mimicking hypertrophic cardiomyopathy in a Turkish family with a novel PRKAG2 mutation.

BAYRAK F., KOMURCU-BAYRAK E., MUTJU B., KAHVECI G., BASARAN Y., Erginel-Unaltuna N.

European journal of heart failure, cilt.8, sa.7, ss.712-5, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 7
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.ejheart.2006.03.006
  • Dergi Adı: European journal of heart failure
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.712-5
  • Anahtar Kelimeler: cardiomyopathy, ventricular pre-excitation, genetics, PARKINSON-WHITE-SYNDROME, DISEASE
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Mutations in PRKAG2, the gene for the gamma 2 regulatory subunit of AMP-activated protein kinase, cause cardiac hypertrophy and electrophysiological abnormalities. We identified a novel mutation in PRKAG2 causing familial ventricular pre-excitation and severe cardiac hypertrophy.