Ventricular pre-excitation and cardiac hypertrophy mimicking hypertrophic cardiomyopathy in a Turkish family with a novel PRKAG2 mutation.


BAYRAK F., KOMURCU-BAYRAK E. , MUTJU B., KAHVECI G., BASARAN Y., Erginel-Unaltuna N.

European journal of heart failure, vol.8, no.7, pp.712-5, 2006 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 7
  • Publication Date: 2006
  • Doi Number: 10.1016/j.ejheart.2006.03.006
  • Journal Name: European journal of heart failure
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.712-5
  • Keywords: cardiomyopathy, ventricular pre-excitation, genetics, PARKINSON-WHITE-SYNDROME, DISEASE

Abstract

Background: Mutations in PRKAG2, the gene for the gamma 2 regulatory subunit of AMP-activated protein kinase, cause cardiac hypertrophy and electrophysiological abnormalities. We identified a novel mutation in PRKAG2 causing familial ventricular pre-excitation and severe cardiac hypertrophy.