THE FAT PAT TISSUE EXPRESSES A PATHOGENIC PROFILE OF INFLAMMATORY MEDIATORIES AND 4-HNE IN PATIENTS WITH OSTEOARTHRITIS

Tanriverdi B., TANRIVERDİ G., Ercin E., DAĞISTANLI F., Ones H. N., Edipoglu E., ...More

ACTA MEDICA MEDITERRANEA, vol.37, no.2, pp.1045-1051, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.19193/0393-6384_2021_2_160
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Page Numbers: pp.1045-1051
  • Istanbul University Affiliated: No

Abstract

Introduction: In this study we aimed to estimate if there is a releation between some inflammatory or adipocyte-derived cytokines as IL-1 beta, IL-6, TNF-alfa, VEGF, 4-HNE, macrophages, mast cells and osteoarthirites. Especially 4-HNE which associated obesity is a new marker for estimating the chondral injuries and there is a poor evidence of it's effect on IFP and osteoarthritis.