4-Vinylbenzene Boronic Acid-Hydroxy Apatite/Polyvinyl Alcohol Based Nanofiber Scaffold Synthesized by UV-Activated Reactive Electrospinning

Deniz, D.; KAHRAMAN, MEMET; Erdem Kuruca, Dürdane; Suleymanoglu, Mediha; Gungor, A.

doi:10.1080/00914037.2014.1002130

4-Vinylbenzene Boronic Acid-Hydroxy Apatite/Polyvinyl Alcohol Based Nanofiber Scaffold Synthesized by UV-Activated Reactive Electrospinning

Deniz D. Y., KAHRAMAN M. V., Erdem Kuruca S., Suleymanoglu M., Gungor A.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, cilt.64, sa.14, ss.727-732, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 64 Sayı: 14
Basım Tarihi: 2015
Doi Numarası: 10.1080/00914037.2014.1002130
Dergi Adı: INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.727-732
İstanbul Üniversitesi Adresli: Evet

Özet

In this study, we prepared photo-crosslinked modified HAP (hydroxy apatite)/polyvinyl alcohol (PVA) composite nanofiber scaffold for cell growth applications. HAP was synthesized and then modified with 4-vinylbenzene boronic acid (VBBA) to obtain 4-VBBA-HAP. By means of the simultaneous UV electrospinning technique 4-VBBA-HAP/PVA composite was obtained. The structure and morphology of electrospun membranes were investigated by scanning electron microscopy) and Fourier transform infrared spectroscopy technique. Nanofibers were treated with collagen solution via the spraying method. For the cell culture applications ECV304 and SAOS cells were seeded on the chosen electrospun fibrous scaffolds.