Association between PTEN IVS4 polymorphism and development of colorectal cancer in a Turkish population

Canbay E., Kahraman O. T., BUĞRA D., Caykara B., Seyhan M. F., Bulut T., ...Daha Fazla

EXPERT OPINION ON THERAPEUTIC TARGETS, cilt.17, sa.1, ss.1-6, 2013 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1517/14728222.2013.727398
  • Dergi Adı: EXPERT OPINION ON THERAPEUTIC TARGETS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1-6
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Phosphatase and tensin homolog (PTEN) is one of the most frequently mutated suppressor genes in human cancers. However, there are no data about the role of PTEN IVS4 polymorphism in development of colorectal cancer (CRC). The authors aimed to determine the role of PTEN IVS4 variants in the etiology of CRC.