Association between PTEN IVS4 polymorphism and development of colorectal cancer in a Turkish population

Canbay E., Kahraman O. T., BUĞRA D., Caykara B., Seyhan M. F., Bulut T., ...More

EXPERT OPINION ON THERAPEUTIC TARGETS, vol.17, no.1, pp.1-6, 2013 (SCI-Expanded) identifier identifier identifier


Background: Phosphatase and tensin homolog (PTEN) is one of the most frequently mutated suppressor genes in human cancers. However, there are no data about the role of PTEN IVS4 polymorphism in development of colorectal cancer (CRC). The authors aimed to determine the role of PTEN IVS4 variants in the etiology of CRC.