Contraindicated Drugs in Exotic Animals
5th International Vet-Istanbul Group Congress & 8th International Scientific Meeting Days of Veterinary Medicine - 2018, Ohrid, Macedonia, 23 - 27 September 2018, pp.67
- Publication Type: Conference Paper / Summary Text
- City: Ohrid
- Country: Macedonia
- Page Numbers: pp.67
- Open Archive Collection: AVESIS Open Access Collection
- Istanbul University Affiliated: Yes
Abstract
“Primum non nocere” (first, to do no harm) can be accepted as a fundamental principle in the treatment of all animals. Mainly in exotic animals, medical treatment without causing harm is one of the major challenges due to many differences in wide variety of species. One of the main reason of challenges arises from that most of the common drugs have not been evaluated pharmacologically in exotic animals especially for pharmacokinetic and pharmacodynamic aspects. Therefore, much of our knowledge about drug usage like dose and frequency or therapeutic effect in exotic animals are based on reported anecdotal evidences, case reports and extrapolation from other species. Also, a drug may cause no harm in some species but could lead to death in another animal. Due to the lack of species-specific studies, there are limited information about drug efficacy, adverse reactions and drug interactions in vivo. This limiting makes it more difficult to determine the treatment success. In addition, the practitioner could not determine the failure of the treatment depends on the patient or the medication errors. When the limitations are considered, exotic animal veterinarians should perform a literature search when using a novel drug in exotic species from the point of evidence-based medicine. This review will focus on drugs that are contraindicated in exotic animals and help exotic veterinarians to select and apply more appropriate drugs to their patients.
Key words: contraindications; antibiotics, antiparasitics, exotic pets