Antibacterial, Antiurease, and Antioxidant Activities of Some Arylidene Barbiturates

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Sokmen B. B., Ugras S., Sarıkaya H. Y., Ugras H. I., Yanardag R.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol.171, no.8, pp.2030-2039, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 171 Issue: 8
• Publication Date: 2013
• Doi Number: 10.1007/s12010-013-0486-6
• Journal Name: APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.2030-2039
• Istanbul University Affiliated: Yes

Abstract

Some series of arylidene barbiturates and thiobarbiturates were evaluated for their antibacterial, antioxidant, and urease inhibition activities. The arylidene barbiturates and thiobarbiturates were tested for antimicrobial activity using the agar well diffusion technique against 13 bacteria. The synthesized compounds (1a-g) were screened for antiurease and antioxidant activities. The results showed that the synthesized compounds (1a-g) had effective antiurease, antioxidant, and antibacterial activities.