THE miR-196a2T/C VARIANT AS A POSSIBLE PREDISPOSING FACTOR FOR ANKYLOSING SPONDYLITIS IN A TURKISH POPULATION2

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Atıf İçin Kopyala

Pehlivan S., Gursoy S., Nursal A. F., Akaltun M. S., Ozdilli K., Pehlivan M.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.83, ss.81-85, 2020 (ESCI)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 83
• Basım Tarihi: 2020
• Doi Numarası: 10.26650/iuitfd.2019.0023
• Dergi Adı: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.81-85
• İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Ankylosing spondylitis (AS) is a chronic inflammatory disorder. MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes. Altered miRNA expression has been implicated in the pathogenesis of several diseases. Therefore, we aimed to explore the effects of miR-196a2T/C (rs11614913) variant profile on susceptibility to AS in a Turkish population.