THE miR-196a2T/C VARIANT AS A POSSIBLE PREDISPOSING FACTOR FOR ANKYLOSING SPONDYLITIS IN A TURKISH POPULATION2

Pehlivan, Sacide; Gursoy, Savas; Nursal, Ayse; Akaltun, Mazlum; Ozdilli, Kursat; Pehlivan, Mustafa

doi:10.26650/iuitfd.2019.0023

THE miR-196a2T/C VARIANT AS A POSSIBLE PREDISPOSING FACTOR FOR ANKYLOSING SPONDYLITIS IN A TURKISH POPULATION2

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Pehlivan S., Gursoy S., Nursal A. F., Akaltun M. S., Ozdilli K., Pehlivan M.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.83, pp.81-85, 2020 (ESCI)

Publication Type: Article / Article
Volume: 83
Publication Date: 2020
Doi Number: 10.26650/iuitfd.2019.0023
Journal Name: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Page Numbers: pp.81-85
Istanbul University Affiliated: Yes

Abstract

Objective: Ankylosing spondylitis (AS) is a chronic inflammatory disorder. MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes. Altered miRNA expression has been implicated in the pathogenesis of several diseases. Therefore, we aimed to explore the effects of miR-196a2T/C (rs11614913) variant profile on susceptibility to AS in a Turkish population.