Macrophage migration inhibitory factor (MIF) gene - 173 G > C polymorphism and its relationship to coronary artery disease and type 2 diabetes
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, vol.47, no.1, pp.29-37, 2019 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 47 Issue: 1
- Publication Date: 2019
- Doi Number: 10.5543/tkda.2018.35005
- Journal Name: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.29-37
- Keywords: Coronary artery disease, macrophage migration inhibitory factor gene, polymorphism, type 2 diabetes mellitus, AUGSBURG CASE-COHORT, GLUCOSE, ASSOCIATION, EXPRESSION, SEVERITY, INSULIN, RISK
- Istanbul University Affiliated: Yes
Abstract
Objective: Recent studies indicate that macrophage migration inhibitory factor (MIF) is a potent proinflammatory cytokine which mediates the inflammatory process during atherosclerosis. The purpose of the study was to investigate an association between MIF gene polymorphism and type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD) in the Turkish population.