Hereditary tyrosinemia type 1 in Turkey: Twenty year single-center experience


Zeybek A. C. A. , Kiykim E. , SOYUÇEN E., Cansever S., Altay S., Zubarioglu T., ...Daha Fazla

PEDIATRICS INTERNATIONAL, cilt.57, ss.281-289, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 57 Konu: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/ped.12503
  • Dergi Adı: PEDIATRICS INTERNATIONAL
  • Sayfa Sayıları: ss.281-289

Özet

BackgroundHereditary tyrosinemia type 1(HT1) is a chronic disorder leading to severe hepatic, renal and peripheral nerve damage if left untreated. Despite nitisinone treatment HT1 still carries the risks of hepatocellular carcinoma (HCC) and neuropsychological outcome.