Copy number profiling of tumor suppressor genes in head and neck cancer

Yalniz Z., Demokan S., Karabulut B., Ulusan M., Suoglu Y., Dalay N.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, cilt.39, sa.2, ss.341-346, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/hed.24593
  • Dergi Adı: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.341-346
  • Anahtar Kelimeler: copy number change, tumor suppressor genes, head and neck cancer, multiplex ligation-dependent probe amplification (MLPA) analysis, tissue inhibitor of metalloproteinase 3 (TIMP3) amplification, SQUAMOUS-CELL CARCINOMA, PROMOTER HYPERMETHYLATION, CHROMOSOMAL-ABERRATIONS, MULTIPLE GENES, TIMP3, AMPLIFICATION, METHYLATION, EXPRESSION, CDKN2A, INSTABILITY
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background. Sensitive and reliable new biomarkers are needed in head and neck cancer to predict the outcome and for therapy that is more effective. Copy number alterations are frequent and play a critical role in cancer.