Investigation of VEGF and IL-8 Gene Polymorphisms in Patients with Differentiated Thyroid Cancer


Kilic I., GÜLDİKEN S., SİPAHİ T., Palabiyik O., Akker M., Celik O., ...More

CLINICAL LABORATORY, vol.62, no.12, pp.2319-2325, 2016 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 62 Issue: 12
  • Publication Date: 2016
  • Doi Number: 10.7754/clin.lab.2016.160403
  • Journal Name: CLINICAL LABORATORY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2319-2325
  • Istanbul University Affiliated: Yes

Abstract

Background: Differentiated thyroid carcinomas (DTC) account for most of the thyroid cancers. The emergence of DTC may be affected by various predisposing genetic alterations and environmental factors The aim of this study was to investigate the role of VEGF C936T and IL-8 A251T gene polymorphisms in the pathogenesis and metastasis of differentiated thyroid cancer.