Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC.
Acta Pharmaceutica Sciencia, cilt.61, sa.3, ss.257-268, 2023 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 61 Sayı: 3
- Basım Tarihi: 2023
- Doi Numarası: 10.23893/1307-2080.aps6117
- Dergi Adı: Acta Pharmaceutica Sciencia
- Derginin Tarandığı İndeksler: Scopus, EMBASE
- Sayfa Sayıları: ss.257-268
- Anahtar Kelimeler: Antibacterial, anticandidal, essential oil, Ferula rigidula, GCMS
- İstanbul Üniversitesi Adresli: Evet
Özet
The hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were characterized rep-resenting 98.2% of the essential oils. The main components of the oil were determined as a-pinene and camphene (24% and 20%, respectively). The anticandidal and antibacterial effects of the essential oil were determined by using partly modi-fied CLSI protocols M27-A2 and M7-A7, respectively. The essential oil of the dried fruits showed several inhibitory effects on the tested bacteria panel (MIC, 62.5 to 2000 µg/mL) and Candida species (MIC, 125 to 1000 µg/mL).