Cytokine gene variants/expressions and non-syndromic microtia - is there a link?

NURSAL A. F., BEKERECİOĞLU M., Pehlivan S., Sever T., Buyukgural B.

ENT UPDATES, vol.7, no.2, pp.62-67, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.2399/jmu.2017002007
  • Journal Name: ENT UPDATES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.62-67
  • Istanbul University Affiliated: Yes

Abstract

Objective: Although many genetic and environmental factors are investigated the etiopathogenesis of microtia, it still remains unclear. We investigated the relationship between the variants/expression of pro-and anti-inflammatory cytokines [interleukin (IL) 6, IL-10, tumor necrosis factor-alpha (TNF-alpha), transforming growth factor beta (TGF-beta 1), interferon gamma (IFN-gamma)] and susceptibility non-syndromic microtia in a Turkish cohort.