MYELOPEROXIDASE AND GLUTAMATE-CYSTEINE LIGASE POLYMORPHISMS IN TYPE 2 DIABETES MELLITUS: A PRELIMINARY STUDY


Eksi Y. E., KARAALI Z. E., Incekara K., Ergen H. A.

JOURNAL OF MEDICAL BIOCHEMISTRY, vol.33, no.2, pp.156-161, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.2478/jomb-2013-0022
  • Journal Name: JOURNAL OF MEDICAL BIOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.156-161
  • Istanbul University Affiliated: Yes

Abstract

Background: Oxidative stress can accompany the physiopathology of diabetes mellitus. Myeloperoxidase and glutamate-cysteine ligase catalytic subunit are two important substances which are connected with the maintaining of the redox balance in the body. In this study, the association between diabetes, lipid levels, myeloperoxidase -463G/A, and the glutamate-cysteine ligase catalytic subunit -3506A/G gene polymorphisms have been investigated.