Effect of pentoxifylline on histopathological changes in steroid-induced osteonecrosis of femoral head: experimental study in chicken

Erken H. Y., Ofluoglu O., Aktas M., Topal C., Yildiz M.

INTERNATIONAL ORTHOPAEDICS, vol.36, no.7, pp.1523-1528, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 7
  • Publication Date: 2012
  • Doi Number: 10.1007/s00264-012-1497-6
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1523-1528
  • Istanbul University Affiliated: Yes


Pentoxifylline (PTX) is a derivative of methylxanthine and is used in peripheral vascular and cerebrovascular diseases for its effect on the regulation of blood circulation. We investigated whether PTX could be beneficial for femoral head osteonecrosis associated with steroid through these effects.