Akademik Veri Yönetim Sistemi
22nd European Congress of Internal Medicine, İstanbul, Türkiye, 6 - 09 Mart 2024, ss.475, (Özet Bildiri)
Purpose: The primary aim of this study is to find out the
prevalence of frailty (a
geriatric syndrome closely
associated with increased
morbidity and mortality)
in older patients
with heart failure
(HF) by using
recently proposed simpler
modified fried frailty
scale (SMFFS). Our secondary aim is to reveal whether SMFFS is useful as
a frailty assessment tool to predict mortality in follow-up.
Methods: This is
a prospective, follow-up
study including internalized and
community-dwelling older adults(≥65
years) with a diagnosis
of HF. SMFFS
was used to
subjectively assess the
frailty phenotype with
five items (i.e.,
involuntary weight loss, exhaustion,
slow gait speed,
poor handgrip strength,
and sedentary behaviour).
Presence of ≥3
items was accepted
as frailty. Cox-regression analysis was performed to identify whether
frailty defined by SMFFS could predict mortality in follow-up.
Findings: Among 101
patients included, 44
(42.8%) were female.
The mean age
was 75.8±7.6 and
frailty prevalence was
63.4%. After a
median follow-up of
580 days, 29
participants died. Among the parameters significantly
associated with mortality in univariate
analyses, only increased
pulmonary artery pressure
(PAB) and frailty
defined by SMFFS
were the predictors
of mortality in older
adults with HF
(HR (95% CI)
were 1.06 (1.01
– 1.09), (p=0.008)
and 17.6 (1.39
– 227.69) (p=0.027);
for PAB and
frailty, respectively) (Table).
Conclusions:
SMFFS succeeded in
predicting mortality in
older adults with HF. Our results
point out that frailty is a game changer in
the prognosis of
HF and SMFFS
can be used
in cardiology and
geriatric practice to
identify individuals vulnerable
to poor outcomes related to HF.
Keywords: frailty, heart failure, mortality, older adults,
sarcopenia