Evaluation and treatment approaches for neurological post-acute sequelae of COVID-19: A consensus statement and scoping review from the global COVID-19 neuro research coalition

Frontera J. A., Guekht A., Allegri R. F., Ashraf M., BAYKAL B., Crivelli L., ...Daha Fazla

Journal of the Neurological Sciences, cilt.454, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 454
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/j.jns.2023.120827
  • Dergi Adı: Journal of the Neurological Sciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Psycinfo
  • Anahtar Kelimeler: COVID-19, Diagnosis, Evaluation, Management, Neurologic, SARS-COV-2, Therapeutics, Therapy, Treatment
  • İstanbul Üniversitesi Adresli: Evet

Özet

Post-acute neurological sequelae of COVID-19 affect millions of people worldwide, yet little data is available to guide treatment strategies for the most common symptoms. We conducted a scoping review of PubMed/Medline from 1/1/2020–4/1/2023 to identify studies addressing diagnosis and treatment of the most common post-acute neurological sequelae of COVID-19 including: cognitive impairment, sleep disorders, headache, dizziness/lightheadedness, fatigue, weakness, numbness/pain, anxiety, depression and post-traumatic stress disorder. Utilizing the available literature and international disease-specific society guidelines, we constructed symptom-based differential diagnoses, evaluation and management paradigms. This pragmatic, evidence-based consensus document may serve as a guide for a holistic approach to post-COVID neurological care and will complement future clinical trials by outlining best practices in the evaluation and treatment of post-acute neurological signs/symptoms.