Oral Gonadotropin-Releasing Hormone Antagonists in the Treatment of Uterine Myomas: A Systematic Review and Network Meta-analysis of Efficacy Parameters and Adverse Effects

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Telek S. B., Gurbuz Z., Kalafat E., Ata B.

JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY, vol.29, no.5, pp.613-625, 2022 (SCI-Expanded)

• Publication Type: Article / Review
• Volume: 29 Issue: 5
• Publication Date: 2022
• Doi Number: 10.1016/j.jmig.2021.12.011
• Journal Name: JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
• Page Numbers: pp.613-625
• Keywords: Abnormal uterine bleeding, GnRH analog, Leiomyomata, Oral GnRH antagonists, Quality of life, Uterine myoma, ELAGOLIX, FIBROIDS, LEIOMYOMAS, MANAGEMENT, BURDEN, WOMEN
• Istanbul University Affiliated: No

Abstract

Objective: The aim of this systematic review is to gather and synthesize evidence regarding the use of oral gonadotrophin-releasing hormone (GnRH) antagonist for the treatment of bleeding associated with uterine myomas.