Factors affecting the success of microdissection testicular sperm extraction in men with non-obstructive azoospermia
Androloji Bülteni, cilt.22, sa.1, ss.12-15, 2020 (Hakemli Dergi)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 1
- Basım Tarihi: 2020
- Doi Numarası: 10.24898/tandro.2020.72473
- Dergi Adı: Androloji Bülteni
- Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.12-15
- İstanbul Üniversitesi Adresli: Evet
Özet
OBJECTIVE: To determine the sperm retrieval rates (SRRs) and predictive factors of patients with non-obstructive azoospermia (NOA) after testicular sperm extraction (TESE)
MATRERIAL and METHODS: A total of 311 patients who were diagnosed with non-obstructive azoospermia (NOA) and underwent TESE were included in this study. Physical examination, hormone values, testicular volumes, and the medical history of all patients were recorded
RESULTS: The mean sperm retrieval rates (SRRs) were 46.7%. These SRRs were 34.2%, 33.3%, 71.4%, 100%, and 100% for Sertoli Cell Only, late maturation arrest, early maturation arrest, hypospermatogenesis, and normal spermatogenesis, respectively (p<0.001). While the mean FSH values were significantly lower in patients with positive mTESE (19.7±12.8 mL/U vs. 25.3±15.5 mL/U, p: 0.001), the mean testicular volumes were larger in patients with positive TESE compared to patients with negative mTESE (p: 0.004).
CONCLUSION: The testicular histopathology, level of FSH and testicular volume were identified as independent predictors of SRRs for men with NOA
Keywords: Azoospermia, male infertilite, testicular sperm extraction