The genomic origins of the world's first farmers

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Marchi N., Winkelbach L., Schulz I., Brami M., Hofmanová Z., Blöcher J., ...Daha Fazla

Cell, cilt.185, sa.11, ss.1842, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 185 Sayı: 11
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.cell.2022.04.008
  • Dergi Adı: Cell
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database, DIALNET
  • Sayfa Sayıları: ss.1842
  • Anahtar Kelimeler: ancient genomics, demogenomic modeling, demographic inference, demographic processes, human evolution, Neolithic transition, population admixture, upper Palaeolithic
  • İstanbul Üniversitesi Adresli: Evet

Özet

© 2022 The Author(s)The precise genetic origins of the first Neolithic farming populations in Europe and Southwest Asia, as well as the processes and the timing of their differentiation, remain largely unknown. Demogenomic modeling of high-quality ancient genomes reveals that the early farmers of Anatolia and Europe emerged from a multiphase mixing of a Southwest Asian population with a strongly bottlenecked western hunter-gatherer population after the last glacial maximum. Moreover, the ancestors of the first farmers of Europe and Anatolia went through a period of extreme genetic drift during their westward range expansion, contributing highly to their genetic distinctiveness. This modeling elucidates the demographic processes at the root of the Neolithic transition and leads to a spatial interpretation of the population history of Southwest Asia and Europe during the late Pleistocene and early Holocene.